PI4KB
MOLECULAR TARGETphosphatidylinositol 4-kinase beta
PI4KB (phosphatidylinositol 4-kinase beta) is targeted by 17 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting PI4KB
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | lapatinib | 4.84 | 126 |
| 2 | ruxolitinib | 4.23 | 68 |
| 3 | pi 103 | 4.17 | 64 |
| 4 | pazopanib | 3.69 | 39 |
| 5 | tae 684 | 3.43 | 30 |
| 6 | fedratinib | 3.40 | 29 |
| 7 | buparlisib | 3.40 | 29 |
| 8 | lestaurtinib | 3.04 | 20 |
| 9 | r 406 | 2.83 | 16 |
| 10 | plx 4720 | 2.71 | 14 |
| 11 | torin1 | 2.40 | 10 |
| 12 | azd 6482 | 2.30 | 9 |
| 13 | bimiralisib | 2.30 | 9 |
| 14 | tg100 115 | 2.08 | 7 |
| 15 | rg 547 | 2.08 | 7 |
| 16 | Wortmannin | 1.39 | 3 |
| 17 | torin 1 | 1.10 | 2 |
About PI4KB as a Drug Target
PI4KB (phosphatidylinositol 4-kinase beta) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 17 compounds with documented PI4KB interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
PI4KB inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.