PIK3C3
MOLECULAR TARGETphosphatidylinositol 3-kinase catalytic subunit type 3
PIK3C3 (phosphatidylinositol 3-kinase catalytic subunit type 3) is targeted by 19 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting PIK3C3
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | panobinostat | 4.26 | 70 |
| 2 | dactolisib | 4.25 | 69 |
| 3 | pi 103 | 4.17 | 64 |
| 4 | idelalisib | 4.13 | 61 |
| 5 | buparlisib | 3.40 | 29 |
| 6 | omipalisib | 3.14 | 22 |
| 7 | apitolisib | 2.71 | 14 |
| 8 | sapanisertib | 2.64 | 13 |
| 9 | gedatolisib | 2.56 | 12 |
| 10 | vistusertib | 2.48 | 11 |
| 11 | 3 methyladenine | 2.48 | 11 |
| 12 | torin1 | 2.40 | 10 |
| 13 | bimiralisib | 2.30 | 9 |
| 14 | bgt 226 free base | 2.20 | 8 |
| 15 | pilaralisib | 1.95 | 6 |
| 16 | eganelisib | 1.79 | 5 |
| 17 | torin 1 | 1.10 | 2 |
| 18 | pictilisib | 0.69 | 1 |
| 19 | Wortmannin | 0.69 | 1 |
About PIK3C3 as a Drug Target
PIK3C3 (phosphatidylinositol 3-kinase catalytic subunit type 3) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 19 compounds with documented PIK3C3 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
PIK3C3 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.