PIK3R1
MOLECULAR TARGETphosphoinositide-3-kinase regulatory subunit 1
PIK3R1 (phosphoinositide-3-kinase regulatory subunit 1) is targeted by 10 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting PIK3R1
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | ly 294002 | 4.84 | 126 |
| 2 | buparlisib | 3.40 | 29 |
| 3 | pictilisib | 2.83 | 16 |
| 4 | berzosertib | 2.30 | 9 |
| 5 | Wortmannin | 2.08 | 7 |
| 6 | ly294002 | 1.95 | 6 |
| 7 | alpelisib | 1.79 | 5 |
| 8 | Sirolimus | 1.10 | 2 |
| 9 | torin 1 | 1.10 | 2 |
| 10 | Quercetin | 0.69 | 1 |
About PIK3R1 as a Drug Target
PIK3R1 (phosphoinositide-3-kinase regulatory subunit 1) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 10 compounds with documented PIK3R1 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
PIK3R1 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.