PIP5K1A
MOLECULAR TARGETphosphatidylinositol-4-phosphate 5-kinase type 1 alpha
PIP5K1A (phosphatidylinositol-4-phosphate 5-kinase type 1 alpha) is targeted by 17 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting PIP5K1A
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | tozasertib | 4.33 | 75 |
| 2 | bosutinib | 4.08 | 58 |
| 3 | midostaurin | 3.85 | 46 |
| 4 | nintedanib | 3.61 | 36 |
| 5 | tae 684 | 3.43 | 30 |
| 6 | fedratinib | 3.40 | 29 |
| 7 | dovitinib | 3.09 | 21 |
| 8 | jnj 7706621 | 3.09 | 21 |
| 9 | lestaurtinib | 3.04 | 20 |
| 10 | ruboxistaurin | 2.94 | 18 |
| 11 | r 406 | 2.83 | 16 |
| 12 | pha 665752 | 2.71 | 14 |
| 13 | kw 2449 | 2.64 | 13 |
| 14 | gsk 461364 | 2.40 | 10 |
| 15 | su 014813 | 2.20 | 8 |
| 16 | tg100 115 | 2.08 | 7 |
| 17 | Crizotinib | 0.69 | 1 |
About PIP5K1A as a Drug Target
PIP5K1A (phosphatidylinositol-4-phosphate 5-kinase type 1 alpha) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 17 compounds with documented PIP5K1A interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
PIP5K1A inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.