PPARA
MOLECULAR TARGETperoxisome proliferator activated receptor alpha
PPARA (peroxisome proliferator activated receptor alpha) is targeted by 18 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting PPARA
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | Oleic Acid | 1.79 | 5 |
| 2 | Fenofibrate | 1.79 | 5 |
| 3 | Linoleic Acid | 1.79 | 5 |
| 4 | Bezafibrate | 1.61 | 4 |
| 5 | Pioglitazone | 1.61 | 4 |
| 6 | alpha-Linolenic Acid | 1.39 | 3 |
| 7 | Clofibrate | 1.39 | 3 |
| 8 | Gemfibrozil | 1.39 | 3 |
| 9 | Myristic Acid | 1.39 | 3 |
| 10 | Arachidonic Acid | 1.10 | 2 |
| 11 | Berberine | 1.10 | 2 |
| 12 | Mepentol [Supplementary Concept] | 1.10 | 2 |
| 13 | gamma-Linolenic Acid | 1.10 | 2 |
| 14 | Prostaglandin D2 | 1.10 | 2 |
| 15 | Ursolic Acid | 0.69 | 1 |
| 16 | Aldosterone | 0.69 | 1 |
| 17 | Palmitic Acid | 0.69 | 1 |
| 18 | Troglitazone | 0.69 | 1 |
About PPARA as a Drug Target
PPARA (peroxisome proliferator activated receptor alpha) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 18 compounds with documented PPARA interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
PPARA inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.