What compounds target PPARD?

BiohacksAI has identified 36 compounds that interact with PPARD (peroxisome proliferator activated receptor delta). Top compounds include: Bezafibrate, Dactinomycin, Ethidium, cycloheximide, Clotrimazole. Each compound is ranked by evidence score derived from PubMed bioassay confidence and assay count.

What is PPARD (peroxisome proliferator activated)?

PPARD is peroxisome proliferator activated receptor delta. It is a molecular target for 36 compounds documented in PubMed bioassay data. UniProt ID: BAH02282. NCBI Gene ID: 5467.

PPARD

MOLECULAR TARGET

peroxisome proliferator activated receptor delta

UniProt: BAH02282 NCBI Gene: 546736 compounds

PPARD (peroxisome proliferator activated receptor delta) is targeted by 36 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).

Compounds Targeting PPARD

Ranked by bioassay confidence score (PubChem active assay count × evidence quality).

#	Compound	Confidence	Active Assays
1	Bezafibrate	1.61	4
2	Dactinomycin	1.61	4
3	Ethidium	1.61	4
4	cycloheximide	1.39	3
5	Clotrimazole	1.10	2
6	Hexachlorophene	1.10	2
7	Sodium Dodecyl Sulfate	1.10	2
8	Apigenin 5,7,4'-trihydroxy-flavone,	0.69	1
9	Arachidonic Acid	0.69	1
10	Genistein	0.69	1
11	Oleic Acid	0.69	1
12	Mepentol [Supplementary Concept]	0.69	1
13	Aprepitant	0.69	1
14	Astemizole Antihistamine drug now withdrawn from	0.69	1
15	Bisphenol A-Glycidyl Methacrylate	0.69	1
16	Bortezomib	0.69	1
17	Chlorhexidine	0.69	1
18	Dasatinib	0.69	1
19	Daunorubicin	0.69	1
20	Disulfiram	0.69	1
21	Ethinyl Estradiol	0.69	1
22	Fenofibrate	0.69	1
23	Fluspirilene	0.69	1
24	gamma-Linolenic Acid	0.69	1
25	Idazoxan	0.69	1
26	Linoleic Acid	0.69	1
27	Loratadine	0.69	1
28	Vitamin K 3	0.69	1
29	Myristic Acid	0.69	1
30	Palmitic Acid	0.69	1
31	Promethazine	0.69	1
32	Prostaglandin D2	0.69	1
33	Retinaldehyde	0.69	1
34	Rotenone	0.69	1
35	Spironolactone	0.69	1
36	Sulbactam	0.69	1

About PPARD as a Drug Target

PPARD (peroxisome proliferator activated receptor delta) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 36 compounds with documented PPARD interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.

PPARD inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.