Question 1

What compounds target PREPL?

Accepted Answer

BiohacksAI has identified 8 compounds that interact with PREPL (prolyl endopeptidase like). Top compounds include: myricetin-3-O-galactopyranoside [Supplementary Concept], Metergoline, propionylpromazine hydrochloride, Thioridazine, Tannins Polyphenolic compounds with molecular weights of around 500-3000 daltons and containing enough hydroxyl groups (1-2 per 100 MW) for effective cross linking of other compounds (ASTRINGENTS).. Each compound is ranked by evidence score derived from PubMed bioassay confidence and assay count.

Question 2

What is PREPL (prolyl endopeptidase like)?

Accepted Answer

PREPL is prolyl endopeptidase like. It is a molecular target for 8 compounds documented in PubMed bioassay data. UniProt ID: AAI51237. NCBI Gene ID: 9581.

#	Compound	Confidence	Active Assays
1	myricetin-3-O-galactopyranoside [Supplementary Concept]	1.10	2
2	Metergoline	1.10	2
3	propionylpromazine hydrochloride	1.10	2
4	Thioridazine	1.10	2
5	Tannins Polyphenolic compounds with molecular weights of around 500-3000 daltons and containing enough hydroxyl groups (1-2 per 100 MW) for effective cross linking of other compounds (ASTRINGENTS).	0.69	1
6	Aurintricarboxylic Acid	0.69	1
7	Harmaline	0.69	1
8	Perphenazine	0.69	1

BiohacksAI

PREPL

Compounds Targeting PREPL

About PREPL as a Drug Target