PRKAG3
MOLECULAR TARGETprotein kinase AMP-activated non-catalytic subunit gamma 3
PRKAG3 (protein kinase AMP-activated non-catalytic subunit gamma 3) is targeted by 10 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting PRKAG3
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | Proguanil | 1.95 | 6 |
| 2 | Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone | 1.61 | 4 |
| 3 | Adenosine Monophosphate Adenine nucleotide containing | 1.39 | 3 |
| 4 | Niclosamide | 1.39 | 3 |
| 5 | Ursolic Acid | 1.10 | 2 |
| 6 | Antimycin | 1.10 | 2 |
| 7 | Oleanolic Acid | 1.10 | 2 |
| 8 | Rotenone | 1.10 | 2 |
| 9 | Berberine | 0.69 | 1 |
| 10 | Metformin | 0.69 | 1 |
About PRKAG3 as a Drug Target
PRKAG3 (protein kinase AMP-activated non-catalytic subunit gamma 3) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 10 compounds with documented PRKAG3 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
PRKAG3 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.