PRKN
MOLECULAR TARGETparkin RBR E3 ubiquitin protein ligase
PRKN (parkin RBR E3 ubiquitin protein ligase) is targeted by 7 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting PRKN
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | Apigenin 5,7,4'-trihydroxy-flavone, | 1.10 | 2 |
| 2 | kenpaullone | 1.10 | 2 |
| 3 | Genistein | 0.69 | 1 |
| 4 | amn082 | 0.69 | 1 |
| 5 | Hexachlorophene | 0.69 | 1 |
| 6 | Medroxyprogesterone Acetate | 0.69 | 1 |
| 7 | Nitrendipine | 0.69 | 1 |
About PRKN as a Drug Target
PRKN (parkin RBR E3 ubiquitin protein ligase) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 7 compounds with documented PRKN interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
PRKN inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.