PRKX
MOLECULAR TARGETprotein kinase cAMP-dependent X-linked catalytic subunit
PRKX (protein kinase cAMP-dependent X-linked catalytic subunit) is targeted by 7 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting PRKX
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | midostaurin | 3.85 | 46 |
| 2 | tae 684 | 3.43 | 30 |
| 3 | lestaurtinib | 3.04 | 20 |
| 4 | kw 2449 | 2.64 | 13 |
| 5 | gsk 690693 | 2.64 | 13 |
| 6 | ast 487 | 2.56 | 12 |
| 7 | hydroxyfasudil [Supplementary Concept] | 1.39 | 3 |
About PRKX as a Drug Target
PRKX (protein kinase cAMP-dependent X-linked catalytic subunit) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 7 compounds with documented PRKX interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
PRKX inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.