PSMB5
MOLECULAR TARGETproteasome 20S subunit beta 5
PSMB5 (proteasome 20S subunit beta 5) is targeted by 12 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting PSMB5
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | Bortezomib | 3.99 | 53 |
| 2 | Disulfiram | 1.61 | 4 |
| 3 | 4-Hydroxybenzoate-3-Monooxygenase | 1.61 | 4 |
| 4 | Reserpine | 1.61 | 4 |
| 5 | Apigenin 5,7,4'-trihydroxy-flavone, | 1.10 | 2 |
| 6 | chrysin | 1.10 | 2 |
| 7 | egcg | 1.10 | 2 |
| 8 | Luteolin 5,7,3',4'-tetrahydroxy-flavone, | 1.10 | 2 |
| 9 | Quercetin | 1.10 | 2 |
| 10 | Genistein | 0.69 | 1 |
| 11 | myricetin-3-O-galactopyranoside [Supplementary Concept] | 0.69 | 1 |
| 12 | Emodin Purgative anthraquinone found in several plants, especially RHAMNUS PURSHIANA. It was formerly used as | 0.69 | 1 |
About PSMB5 as a Drug Target
PSMB5 (proteasome 20S subunit beta 5) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 12 compounds with documented PSMB5 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
PSMB5 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.