What compounds target PTK6?

BiohacksAI has identified 41 compounds that interact with PTK6 (protein tyrosine kinase 6). Top compounds include: gefitinib, sb 203580, ibrutinib, cabozantinib, foretinib. Each compound is ranked by evidence score derived from PubMed bioassay confidence and assay count.

What is PTK6 (protein tyrosine kinase)?

PTK6 is protein tyrosine kinase 6. It is a molecular target for 41 compounds documented in PubMed bioassay data. UniProt ID: Q13882. NCBI Gene ID: 5753.

PTK6

MOLECULAR TARGET

protein tyrosine kinase 6

UniProt: Q13882 NCBI Gene: 575341 compounds

PTK6 (protein tyrosine kinase 6) is targeted by 41 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).

Compounds Targeting PTK6

Ranked by bioassay confidence score (PubChem active assay count × evidence quality).

#	Compound	Confidence	Active Assays
1	gefitinib	5.67	290
2	sb 203580	4.92	136
3	ibrutinib	4.86	128
4	cabozantinib	4.39	80
5	foretinib	4.34	76
6	vandetanib	4.30	73
7	brigatinib	3.81	44
8	pazopanib	3.69	39
9	vatalanib	3.69	39
10	sb 202190	3.64	37
11	canertinib	3.53	33
12	tae 684	3.43	30
13	fedratinib	3.40	29
14	saracatinib	3.33	27
15	dabrafenib	3.30	26
16	entrectinib	3.18	23
17	at 9283	3.09	21
18	dasatinib anhydrous	3.09	21
19	lestaurtinib	3.04	20
20	lenvatinib	3.04	20
21	defosbarasertib	2.89	17
22	r 406	2.83	16
23	cediranib	2.83	16
24	plx 4720	2.71	14
25	tivozanib	2.64	13
26	zanubrutinib	2.56	12
27	raf 265	2.48	11
28	motesanib	2.48	11
29	mk 5108	2.48	11
30	entospletinib	2.48	11
31	azd 7762	2.30	9
32	rebastinib	2.20	8
33	gsk 1070916	2.20	8
34	golvatinib	2.20	8
35	tg100 115	2.08	7
36	asp 3026	2.08	7
37	glesatinib	2.08	7
38	sapitinib	1.95	6
39	osi 632	1.79	5
40	Dasatinib	1.61	4
41	Vemurafenib	0.69	1

About PTK6 as a Drug Target

PTK6 (protein tyrosine kinase 6) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 41 compounds with documented PTK6 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.

PTK6 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.