SENP8
MOLECULAR TARGETSUMO peptidase family member, NEDD8 specific
SENP8 (SUMO peptidase family member, NEDD8 specific) is targeted by 20 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting SENP8
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | Apigenin 5,7,4'-trihydroxy-flavone, | 1.39 | 3 |
| 2 | Resveratrol | 1.39 | 3 |
| 3 | amlexanox | 1.39 | 3 |
| 4 | Emodin Purgative anthraquinone found in several plants, especially RHAMNUS PURSHIANA. It was formerly used as | 1.39 | 3 |
| 5 | tyrphostin ag 1295 | 1.39 | 3 |
| 6 | Leflunomide | 1.10 | 2 |
| 7 | piceatannol | 1.10 | 2 |
| 8 | Carnitine | 0.69 | 1 |
| 9 | Methylene Blue | 0.69 | 1 |
| 10 | myricetin-3-O-galactopyranoside [Supplementary Concept] | 0.69 | 1 |
| 11 | Carbidopa | 0.69 | 1 |
| 12 | Deferoxamine Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as | 0.69 | 1 |
| 13 | Edaravone | 0.69 | 1 |
| 14 | Ethidium | 0.69 | 1 |
| 15 | Lithocholic Acid | 0.69 | 1 |
| 16 | Niclosamide | 0.69 | 1 |
| 17 | ninhydrin | 0.69 | 1 |
| 18 | Noscapine | 0.69 | 1 |
| 19 | streptonigrin | 0.69 | 1 |
| 20 | tyrphostin 9 | 0.69 | 1 |
About SENP8 as a Drug Target
SENP8 (SUMO peptidase family member, NEDD8 specific) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 20 compounds with documented SENP8 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
SENP8 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.