ST14
MOLECULAR TARGETST14 transmembrane serine protease matriptase
ST14 (ST14 transmembrane serine protease matriptase) is targeted by 6 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting ST14
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | leupeptin | 3.40 | 29 |
| 2 | nafamostat | 3.00 | 19 |
| 3 | hexamidine | 1.95 | 6 |
| 4 | Rivaroxaban | 0.69 | 1 |
| 5 | pentamidine | 0.69 | 1 |
| 6 | bdb chembl4093566 | 0.69 | 1 |
About ST14 as a Drug Target
ST14 (ST14 transmembrane serine protease matriptase) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 6 compounds with documented ST14 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
ST14 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.