What compounds target TBXAS1?

BiohacksAI has identified 28 compounds that interact with TBXAS1 (thromboxane A synthase 1). Top compounds include: tamoxifen, imatinib, nifedipine, saquinavir, sb 203580. Each compound is ranked by evidence score derived from PubMed bioassay confidence and assay count.

What is TBXAS1 (thromboxane A synthase)?

TBXAS1 is thromboxane A synthase 1. It is a molecular target for 28 compounds documented in PubMed bioassay data. UniProt ID: P24557. NCBI Gene ID: 6916.

TBXAS1

MOLECULAR TARGET

thromboxane A synthase 1

UniProt: P24557 NCBI Gene: 691628 compounds

TBXAS1 (thromboxane A synthase 1) is targeted by 28 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).

Compounds Targeting TBXAS1

Ranked by bioassay confidence score (PubChem active assay count × evidence quality).

#	Compound	Confidence	Active Assays
1	tamoxifen	5.88	358
2	imatinib	5.47	236
3	nifedipine	5.34	208
4	saquinavir	4.98	144
5	sb 203580	4.92	136
6	indinavir	4.84	125
7	alpha naphthoflavone	4.67	106
8	amprenavir	4.64	103
9	nelfinavir	4.51	90
10	aminoglutethimide	4.11	60
11	diethylstilbestrol	4.06	57
12	zafirlukast	3.89	48
13	trovafloxacin	3.64	37
14	candesartan	3.47	31
15	fpl 55712	3.18	23
16	bithionol	2.89	17
17	benzylimidazole	2.89	17
18	closantel	2.71	14
19	sulotroban	2.64	13
20	sulconazole	2.48	11
21	oxiconazole	2.48	11
22	lacidipine	2.40	10
23	e isbogrel	2.30	9
24	ridogrel	2.30	9
25	cetylpyridinium bromide	2.20	8
26	ergocornine	1.95	6
27	3345 tetrachlorosalicylanilide	1.95	6
28	Indomethacin	0.69	1

About TBXAS1 as a Drug Target

TBXAS1 (thromboxane A synthase 1) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 28 compounds with documented TBXAS1 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.

TBXAS1 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.