TGFBR1
MOLECULAR TARGETtransforming growth factor beta receptor 1
TGFBR1 (transforming growth factor beta receptor 1) is targeted by 25 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting TGFBR1
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | sb 203580 | 4.92 | 136 |
| 2 | tozasertib | 4.33 | 75 |
| 3 | nintedanib | 3.61 | 36 |
| 4 | canertinib | 3.53 | 33 |
| 5 | tae 684 | 3.43 | 30 |
| 6 | saracatinib | 3.33 | 27 |
| 7 | sb 431542 | 3.33 | 27 |
| 8 | dabrafenib | 3.30 | 26 |
| 9 | dorsomorphin | 3.14 | 22 |
| 10 | at 9283 | 3.09 | 21 |
| 11 | lestaurtinib | 3.04 | 20 |
| 12 | danusertib | 2.94 | 18 |
| 13 | galunisertib | 2.94 | 18 |
| 14 | momelotinib | 2.89 | 17 |
| 15 | r 406 | 2.83 | 16 |
| 16 | k 252a | 2.83 | 16 |
| 17 | cediranib | 2.83 | 16 |
| 18 | mk 5108 | 2.48 | 11 |
| 19 | vactosertib | 2.40 | 10 |
| 20 | gsk 1070916 | 2.20 | 8 |
| 21 | cyc 116 | 2.08 | 7 |
| 22 | osi 027 | 2.08 | 7 |
| 23 | osi 632 | 1.79 | 5 |
| 24 | Crizotinib | 0.69 | 1 |
| 25 | Dasatinib | 0.69 | 1 |
About TGFBR1 as a Drug Target
TGFBR1 (transforming growth factor beta receptor 1) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 25 compounds with documented TGFBR1 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
TGFBR1 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.