TGFBR2
MOLECULAR TARGETtransforming growth factor beta receptor 2
TGFBR2 (transforming growth factor beta receptor 2) is targeted by 24 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting TGFBR2
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | sb 203580 | 4.92 | 136 |
| 2 | alvocidib | 4.52 | 91 |
| 3 | ponatinib | 4.26 | 70 |
| 4 | pazopanib | 3.69 | 39 |
| 5 | canertinib | 3.53 | 33 |
| 6 | bms 387032 | 3.47 | 31 |
| 7 | tae 684 | 3.43 | 30 |
| 8 | fedratinib | 3.40 | 29 |
| 9 | sb 431542 | 3.33 | 27 |
| 10 | dabrafenib | 3.30 | 26 |
| 11 | dorsomorphin | 3.14 | 22 |
| 12 | at 9283 | 3.09 | 21 |
| 13 | lestaurtinib | 3.04 | 20 |
| 14 | danusertib | 2.94 | 18 |
| 15 | galunisertib | 2.94 | 18 |
| 16 | r 406 | 2.83 | 16 |
| 17 | plx 4720 | 2.71 | 14 |
| 18 | enmd 2076 | 2.71 | 14 |
| 19 | ast 487 | 2.56 | 12 |
| 20 | cyc 116 | 2.08 | 7 |
| 21 | Dasatinib | 0.69 | 1 |
| 22 | Hesperidin | 0.69 | 1 |
| 23 | Sorafenib | 0.69 | 1 |
| 24 | Vemurafenib | 0.69 | 1 |
About TGFBR2 as a Drug Target
TGFBR2 (transforming growth factor beta receptor 2) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 24 compounds with documented TGFBR2 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
TGFBR2 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.