TRPA1
MOLECULAR TARGETtransient receptor potential cation channel, subfamily A, member 1
TRPA1 (transient receptor potential cation channel, subfamily A, member 1) is targeted by 23 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting TRPA1
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | acrolein | 1.79 | 5 |
| 2 | Resveratrol | 1.61 | 4 |
| 3 | juglone hydroxylase [Supplementary Concept] catalyzes | 1.61 | 4 |
| 4 | Nicotine Nicotine is highly toxic alkaloid. It is | 1.61 | 4 |
| 5 | cbd | 1.39 | 3 |
| 6 | plumbagin [Supplementary Concept] | 1.39 | 3 |
| 7 | cannabidiol | 1.39 | 3 |
| 8 | Pyruvaldehyde | 1.39 | 3 |
| 9 | cyclohexyl carbamic acid 3'-carbamoylbiphenyl-3-yl ester [Supplementary Concept] | 1.39 | 3 |
| 10 | pterostilbene | 1.10 | 2 |
| 11 | Acetaldehyde | 1.10 | 2 |
| 12 | Formaldehyde | 1.10 | 2 |
| 13 | Iodoacetamide | 1.10 | 2 |
| 14 | Masoprocol | 1.10 | 2 |
| 15 | Dehydroepiandrosterone Sulfate | 0.69 | 1 |
| 16 | auraptene | 0.69 | 1 |
| 17 | Camphor | 0.69 | 1 |
| 18 | diallyl trisulfide | 0.69 | 1 |
| 19 | Disulfiram | 0.69 | 1 |
| 20 | Gentamicins | 0.69 | 1 |
| 21 | Niflumic Acid | 0.69 | 1 |
| 22 | Nitrendipine | 0.69 | 1 |
| 23 | Probenecid | 0.69 | 1 |
About TRPA1 as a Drug Target
TRPA1 (transient receptor potential cation channel, subfamily A, member 1) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 23 compounds with documented TRPA1 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
TRPA1 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.