What compounds target VDR?

BiohacksAI has identified 79 compounds that interact with VDR (vitamin D receptor). Top compounds include: Calcitriol, Lithocholic Acid, Cholecalciferol Derivative of 7-dehydroxycholesterol formed by ULTRAVIOLET RAYS breaking of, Disulfiram, Ethidium. Each compound is ranked by evidence score derived from PubMed bioassay confidence and assay count.

What is VDR (vitamin D receptor)?

VDR is vitamin D receptor. It is a molecular target for 79 compounds documented in PubMed bioassay data. UniProt ID: BAH02291. NCBI Gene ID: 7421.

VDR

MOLECULAR TARGET

vitamin D receptor

UniProt: BAH02291 NCBI Gene: 742179 compounds

VDR (vitamin D receptor) is targeted by 79 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).

Compounds Targeting VDR

Ranked by bioassay confidence score (PubChem active assay count × evidence quality).

#	Compound	Confidence	Active Assays
1	Calcitriol	4.65	104
2	Lithocholic Acid	2.56	12
3	Cholecalciferol Derivative of 7-dehydroxycholesterol formed by ULTRAVIOLET RAYS breaking of	1.95	6
4	Disulfiram	1.61	4
5	Ethidium	1.61	4
6	Oxyphenbutazone	1.61	4
7	Dactinomycin	1.39	3
8	Nisoldipine	1.39	3
9	Apigenin 5,7,4'-trihydroxy-flavone,	1.10	2
10	Arachidonic Acid	1.10	2
11	Dehydroepiandrosterone Sulfate	1.10	2
12	plumbagin [Supplementary Concept]	1.10	2
13	alpha-Linolenic Acid	1.10	2
14	Dinitrochlorobenzene	1.10	2
15	Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone	1.10	2
16	Idazoxan	1.10	2
17	juglone hydroxylase [Supplementary Concept] catalyzes	1.10	2
18	Vitamin K 3	1.10	2
19	Podophyllotoxin	1.10	2
20	Sodium Dodecyl Sulfate	1.10	2
21	Wortmannin	1.10	2
22	Catechin	0.69	1
23	chrysin	0.69	1
24	Night Vision Function of	0.69	1
25	Methotrexate	0.69	1
26	Amoxapine	0.69	1
27	Aurintricarboxylic Acid	0.69	1
28	Bromocriptine	0.69	1
29	C75-coenzyme	0.69	1
30	Calcifediol	0.69	1
31	Calcimycin	0.69	1
32	candesartan cilexetil [Supplementary Concept]	0.69	1
33	Carbaryl	0.69	1
34	salvin [Supplementary Concept]	0.69	1
35	cefaclor	0.69	1
36	Cefpirome	0.69	1
37	Colchicine	0.69	1
38	cycloheximide	0.69	1
39	d609	0.69	1
40	Daunorubicin	0.69	1
41	diallyl trisulfide	0.69	1
42	Diamide	0.69	1
43	Edaravone	0.69	1
44	Emetine	0.69	1
45	Epinephrine	0.69	1
46	Estramustine	0.69	1
47	Ethoxyquin Antioxidant; also	0.69	1
48	Feprazone	0.69	1
49	gamma-Linolenic Acid	0.69	1
50	Gliotoxin	0.69	1

Showing top 50 of 79 compounds. Use the BiohacksAI search to explore all VDR modulators.

About VDR as a Drug Target

VDR (vitamin D receptor) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 79 compounds with documented VDR interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.

VDR inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.