XDH
MOLECULAR TARGETxanthine dehydrogenase
XDH (xanthine dehydrogenase) is targeted by 12 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting XDH
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | Febuxostat | 2.71 | 14 |
| 2 | Quercetin | 2.08 | 7 |
| 3 | Apigenin 5,7,4'-trihydroxy-flavone, | 1.39 | 3 |
| 4 | Luteolin 5,7,3',4'-tetrahydroxy-flavone, | 1.39 | 3 |
| 5 | chrysin | 1.10 | 2 |
| 6 | Oxypurinol | 1.10 | 2 |
| 7 | fisetin | 0.69 | 1 |
| 8 | Genistein | 0.69 | 1 |
| 9 | Kaempferols | 0.69 | 1 |
| 10 | myricetin-3-O-galactopyranoside [Supplementary Concept] | 0.69 | 1 |
| 11 | Hesperidin | 0.69 | 1 |
| 12 | isorhamnetin-3-O-beta-D-glucopyranosyl-(1-3)-alpha-L-rhamnopyranosyl-(1-6)-beta-D-galactopyranoside [Supplementary Concept] from | 0.69 | 1 |
About XDH as a Drug Target
XDH (xanthine dehydrogenase) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 12 compounds with documented XDH interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
XDH inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.