What compounds affect the Regulation of NPAS4 gene expression pathway?

151 compounds in the BiohacksAI corpus have documented interactions with genes in the Regulation of NPAS4 gene expression pathway (Reactome ID: R-HSA-9768759). These compounds target 2 genes within this pathway.

What genes are in the Regulation of NPAS4 gene expression pathway?

The Regulation of NPAS4 gene expression pathway involves 2 genes. Key genes include: AGO2, NR3C1.

Regulation of NPAS4 gene expression

REACTOME PATHWAY

Reactome: R-HSA-97687592 genes151 compounds

The Regulation of NPAS4 gene expression pathway (Reactome ID: R-HSA-9768759) involves 2 genes and is affected by 151 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.

Genes in this Pathway

AGO2 NR3C1

Compounds Affecting Regulation of NPAS4 gene expression

#	Compound	Targets Hit	Studies
1	Prednisolone	—	1,000
2	Hydrocortisone	—	299
3	Corticosterone	—	300
4	Hydrocortisone	—	298
5	Budesonide	—	1,000
6	Triamcinolone Acetonide	—	300
7	Megestrol Acetate Megestrol acetate is	—	300
8	Methyltestosterone	—	300
9	Prednisone	—	298
10	Triamcinolone	—	300
11	Medroxyprogesterone Acetate	—	299
12	Methylprednisolone	—	299
13	Progesterone	—	299
14	17 alpha-Hydroxyprogesterone Caproate Hydroxyprogesterone derivative that acts as	—	287
15	Androstenedione	—	300
16	Azacitidine	—	298
17	Azacitidine	—	300
18	Betamethasone	—	299
19	Cortisone	—	299
20	Desoxycorticosterone	—	300
21	Dihydrotestosterone	—	300
22	Fluocinolone Acetonide	—	295
23	Fluorometholone	—	299
24	Fluoxymesterone	—	278
25	Nandrolone C18 steroid with androgenic and anabolic properties. It is generally prepared from alkyl ethers of ESTRADIOL to resemble TESTOSTERONE but less	—	300
26	Testosterone Propionate	—	300
27	Beclomethasone	—	300
28	cycloheximide	—	300
29	Ethinyl Estradiol	—	300
30	Fludrocortisone	—	299
31	Flurandrenolone	—	65
32	Norethindrone	—	300
33	Dehydroepiandrosterone	—	300
34	Testosterone	—	299
35	17-alpha-Hydroxyprogesterone	—	300
36	Chlormadinone Acetate	—	300
37	Danazol	—	298
38	Dehydroepiandrosterone	—	300
39	auricularum [Supplementary Concept] combination of above three antibiotics and dexamethasone 21-phosphate; used in	—	148
40	Dydrogesterone	—	300
41	Estriol	—	300
42	Estrone	—	300
43	Ethisterone 17 alpha-Hydroxypregn-4-en-20-yn-3-one.	—	119
44	Fluocinonide	—	196
45	Fluprednisolone	—	31
46	Fulvestrant	—	295
47	Levonorgestrel	—	292
48	Medroxyprogesterone	—	298
49	Melengestrol Acetate	—	300
50	Norgestrel	—	300

About the Regulation of NPAS4 gene expression Pathway

The Regulation of NPAS4 gene expression pathway is catalogued in Reactome (ID: R-HSA-9768759) and involves 2 genes. In the BiohacksAI corpus, 151 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include AGO2, NR3C1.