Compounds That Target AKT1
Akt serine/threonine kinase 1 · 20 compounds in BiohacksAI corpus
AKT1 (protein kinase B alpha) is a central node in the PI3K/AKT/mTOR signaling pathway governing cell survival, proliferation, and glucose metabolism. It is overactivated in numerous cancers and metabolic diseases. The 20 compounds targeting AKT1 span pharmaceutical kinase inhibitors and natural compounds including curcumin, quercetin, and resveratrol, which show evidence of AKT pathway modulation.
The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for AKT1 (Akt serine/threonine kinase 1). Confidence scores reflect the strength and breadth of experimental evidence.
Explore related resources: AKT1 target overview · All biological targets · Biological pathways
Data from BindingDB and PubMed. For research purposes only. Not medical advice.