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BiohacksAI/Pathways/Circadian Rhythm
PATHWAYCellular Defense

Circadian Rhythm

Biological clock regulation — disruption accelerates aging, affects metabolism and DNA repair

1,135 compounds · BiohacksAI corpus

1,135
compounds
Compounds
1,135
Category
Cellular Defense
Pathway ID
CIRCADIAN
MeSH Terms
Circadian RhythmCLOCK ProteinsPeriod Circadian RegulatorCryptochromeMelatoninBiological Clocks
Top Compounds — Circadian Rhythm (50 of 1,135)
1
Amlodipine
1,000
studies
75.7
evidence
2
Losartan
1,000
studies
75.0
evidence
3
Metoprolol
1,000
studies
75.7
evidence
4
Budesonide
1,000
studies
80.1
evidence
5
Sertraline
1,000
studies
76.2
evidence
6
Venlafaxine
1,000
studies
74.1
evidence
7
Salbutamol
297
studies
76.1
evidence
8
Insulin
1,000
studies
70.5
evidence
9
Fluoxetine
1,000
studies
75.8
evidence
10
Prednisolone
1,000
studies
79.5
evidence
11
Naproxen
1,000
studies
74.8
evidence
12
Metformin
1,000
studies
73.5
evidence
13
Ciprofloxacin
1,000
studies
73.7
evidence
14
Ibuprofen
1,000
studies
78.8
evidence
15
Tramadol
1,000
studies
77.9
evidence
16
Diazepam
999
studies
73.0
evidence
17
Liraglutide
999
studies
76.7
evidence
18
Pregabalin
996
studies
77.1
evidence
19
Empagliflozin
996
studies
73.3
evidence
20
Escitalopram
995
studies
74.8
evidence
21
Quetiapine
994
studies
73.6
evidence
22
Levothyroxine
994
studies
64.3
evidence
23
Duloxetine
993
studies
73.0
evidence
24
Sitagliptin
990
studies
72.1
evidence
25
Montelukast
985
studies
69.1
evidence
26
Lisinopril
904
studies
68.6
evidence
27
Neuropeptide_y
500
studies
44.2
evidence
28
Cucumis_sativus
500
studies
40.0
evidence
29
Cynodon_dactylon
500
studies
40.5
evidence
30
Prunus_avium
500
studies
42.2
evidence
31
Portulaca_oleracea
500
studies
38.3
evidence
32
Cajanus_cajan
500
studies
39.9
evidence
33
Cucumis_melo
500
studies
41.4
evidence
34
Eucalyptus_globulus
500
studies
39.6
evidence
35
Galanin
500
studies
43.1
evidence
36
Vitis_vinifera
500
studies
40.1
evidence
37
Allium_sativum
500
studies
39.1
evidence
38
Azadirachta_indica
500
studies
37.0
evidence
39
Brassica_campestris
500
studies
40.0
evidence
40
Citrus_limon
500
studies
39.0
evidence
41
Curcuma_longa
500
studies
39.8
evidence
42
Hibiscus_sabdariffa
500
studies
41.3
evidence
43
Lepidium_sativum
500
studies
36.5
evidence
44
Saccharum_officinarum
500
studies
42.1
evidence
45
Solanum_nigrum
500
studies
36.7
evidence
46
Trigonella_foenum
499
studies
39.0
evidence
47
Hordeum_vulgare
499
studies
39.9
evidence
48
Lens_culinaris
499
studies
43.8
evidence
49
Ricinus_communis
499
studies
37.5
evidence
50
Tinospora_cordifolia
499
studies
38.1
evidence

Data from PubMed, BindingDB, and Reactome. Not medical advice.