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BiohacksAI/Pathways/Oxidative Stress / Nrf2
PATHWAYCellular Defense

Oxidative Stress / Nrf2

ROS management and antioxidant defense — Nrf2/ARE pathway central to cellular resilience

3,333 compounds · BiohacksAI corpus

3,333
compounds
Compounds
3,333
Category
Cellular Defense
Pathway ID
OXIDATIVE_STRESS
MeSH Terms
Oxidative StressReactive Oxygen SpeciesNF-E2-Related Factor 2Nrf2AntioxidantsGlutathioneSuperoxide DismutaseCatalaseHeme Oxygenase-1NADPH Oxidase
Top Compounds — Oxidative Stress / Nrf2 (50 of 3,333)
1
Simvastatin
1,000
studies
73.6
evidence
2
Losartan
1,000
studies
75.0
evidence
3
Metformin
1,000
studies
73.5
evidence
4
Insulin
1,000
studies
70.5
evidence
5
Metoprolol
1,000
studies
75.7
evidence
6
Paracetamol
1,000
studies
77.1
evidence
7
Aspirin
1,000
studies
69.5
evidence
8
Atorvastatin
1,000
studies
76.1
evidence
9
Warfarin
1,000
studies
65.0
evidence
10
Amlodipine
1,000
studies
75.7
evidence
11
Amoxicillin
1,000
studies
79.4
evidence
12
Azithromycin
1,000
studies
78.3
evidence
13
Prednisolone
1,000
studies
79.5
evidence
14
Rituximab
1,000
studies
74.1
evidence
15
Salbutamol
297
studies
76.1
evidence
16
Venlafaxine
1,000
studies
74.1
evidence
17
Doxycycline
999
studies
76.8
evidence
18
Diazepam
999
studies
73.0
evidence
19
Liraglutide
999
studies
76.7
evidence
20
Semaglutide
999
studies
69.9
evidence
21
Pregabalin
996
studies
77.1
evidence
22
Empagliflozin
996
studies
73.3
evidence
23
Escitalopram
995
studies
74.8
evidence
24
Levothyroxine
994
studies
64.3
evidence
25
Duloxetine
993
studies
73.0
evidence
26
Sitagliptin
990
studies
72.1
evidence
27
Montelukast
985
studies
69.1
evidence
28
Lisinopril
904
studies
68.6
evidence
29
Hibiscus_sabdariffa
500
studies
41.3
evidence
30
Moringa_oleifera
500
studies
37.8
evidence
31
Ocimum_sanctum
500
studies
38.1
evidence
32
Punica_granatum
500
studies
38.3
evidence
33
Nelumbo__nucifera
500
studies
39.5
evidence
34
Nelumbo_nucifera
500
studies
39.5
evidence
35
Terminalia_chebula
500
studies
39.0
evidence
36
Syzygium_aromaticum
500
studies
37.4
evidence
37
Portulaca_oleracea
500
studies
38.3
evidence
38
Crocus_sativus
500
studies
40.6
evidence
39
Juglans_regia
500
studies
38.7
evidence
40
Phoenix__dactylifera
500
studies
38.3
evidence
41
Phoenix_dactylifera
500
studies
38.3
evidence
42
Solanum_nigrum
500
studies
36.7
evidence
43
Curcuma_longa
500
studies
39.8
evidence
44
Cymbopogon_citratus
500
studies
37.4
evidence
45
Citrus_limon
500
studies
39.0
evidence
46
Allium_sativum
500
studies
39.1
evidence
47
Mangifera_indica
500
studies
38.0
evidence
48
Raphanus_sativus
500
studies
38.0
evidence
49
Momordica_charantia
500
studies
38.6
evidence
50
Vitis_vinifera
500
studies
40.1
evidence

Data from PubMed, BindingDB, and Reactome. Not medical advice.