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Compounds Similar to Avapritinib

10 compounds with shared biological targets · BiohacksAI corpus v20260307-01

The compounds below share molecular targets and biological mechanisms with Avapritinib, including interactions with KIT, PLATELET-DERIVED, ABL1. Similarity is calculated using target-weighted Jaccard scoring across the BiohacksAI BindingDB corpus. Higher shared target counts indicate stronger mechanistic overlap.

Similar Compounds — Ranked by Target Overlap
1
mebendazole
2
shared
25%
overlap
2
su
3
shared
25%
overlap
3
verubulin
2
shared
24%
overlap
4
ag1295
2
shared
24%
overlap
5
sunitinib
2
shared
23%
overlap
6
semaxanib
4
shared
21%
overlap
7
tyrphostin
2
shared
21%
overlap
8
sotuletinib
2
shared
19%
overlap
9
pexidartinib
3
shared
17%
overlap
10
osi
2
shared
15%
overlap
Shared Biological Targets

Click a target to see all compounds with interactions at that molecular target.

Similarity between compounds is computed using IDF-weighted Jaccard scoring across shared molecular targets in the BiohacksAI BindingDB corpus. Compounds with higher overlap scores share more targets, weighted by how specific those targets are across the entire corpus.

Explore related resources: Avapritinib full profile · Browse all compounds · Biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.