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BiohacksAI/Compounds/Bicuculline/Similar

Compounds Similar to Bicuculline

10 compounds with shared biological targets · BiohacksAI corpus v20260307-01

The compounds below share molecular targets and biological mechanisms with Bicuculline, including interactions with GABRA1, GABRA2, GABRA3. Similarity is calculated using target-weighted Jaccard scoring across the BiohacksAI BindingDB corpus. Higher shared target counts indicate stronger mechanistic overlap.

View Bicuculline profile →CALCIUM SIGNALING pathwayDOPAMINE SEROTONIN pathway
Similar Compounds — Ranked by Target Overlap
1
Pregnanolone
17
shared
298
studies
74%
overlap
2
Etomidate
16
shared
299
studies
63%
overlap
3
Ciprofloxacin
15
shared
1,000
studies
63%
overlap
4
Etiocholanolone
16
shared
300
studies
60%
overlap
5
Picrotoxincomplex mixture
16
shared
300
studies
53%
overlap
6
Androsterone
16
shared
300
studies
50%
overlap
7
gamma-Aminobutyric
18
shared
300
studies
40%
overlap
8
Ondansetron
16
shared
299
studies
35%
overlap
9
flumazenil
6
shared
26%
overlap
10
abecarnil
6
shared
26%
overlap
Shared Biological Targets
ESR1ARGABRA1GABRA2GABRA3GABRB2GABRG2CYP11B1

Click a target to see all compounds with interactions at that molecular target.

Similarity between compounds is computed using IDF-weighted Jaccard scoring across shared molecular targets in the BiohacksAI BindingDB corpus. Compounds with higher overlap scores share more targets, weighted by how specific those targets are across the entire corpus.

Explore related resources: Bicuculline full profile · Browse all compounds · Biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.