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BiohacksAI/Compounds/Cortisol/Similar

Compounds Similar to Cortisol

10 compounds with shared biological targets · BiohacksAI corpus v20260307-01

The compounds below share molecular targets and biological mechanisms with Cortisol, including interactions with NR3C1, AR, PGR. Similarity is calculated using target-weighted Jaccard scoring across the BiohacksAI BindingDB corpus. Higher shared target counts indicate stronger mechanistic overlap.

View Cortisol profile →CORTISOL STRESS pathwayTESTOSTERONE HORMONES pathway
Similar Compounds — Ranked by Target Overlap
1
Hydrocortisone
16
shared
298
studies
79%
overlap
2
stanolone
6
shared
35%
overlap
3
Pregnenolone
8
shared
300
studies
30%
overlap
4
Melengestrol
9
shared
300
studies
29%
overlap
5
17-alpha-Hydroxyprogesterone
8
shared
300
studies
28%
overlap
6
Fludrocortisone
6
shared
299
studies
27%
overlap
7
Fluorometholone
8
shared
299
studies
27%
overlap
8
Androstenedione
8
shared
300
studies
27%
overlap
9
Flumethasone
7
shared
179
studies
27%
overlap
10
Methandrostenolone
7
shared
300
studies
27%
overlap
Shared Biological Targets
NR3C1ARNUCLEARPGRCHAINESR1ESR2CYP3A7

Click a target to see all compounds with interactions at that molecular target.

Similarity between compounds is computed using IDF-weighted Jaccard scoring across shared molecular targets in the BiohacksAI BindingDB corpus. Compounds with higher overlap scores share more targets, weighted by how specific those targets are across the entire corpus.

Explore related resources: Cortisol full profile · Browse all compounds · Biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.