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Compounds Similar to Diphenhydramine Hcl

10 compounds with shared biological targets · BiohacksAI corpus v20260307-01

The compounds below share molecular targets and biological mechanisms with Diphenhydramine Hcl, including interactions with CHRM1, HTR2A, CYP2D6. Similarity is calculated using target-weighted Jaccard scoring across the BiohacksAI BindingDB corpus. Higher shared target counts indicate stronger mechanistic overlap.

Similar Compounds — Ranked by Target Overlap
1
Loxapine
10
shared
30
studies
31%
overlap
7
shared
300
studies
24%
overlap
6
shared
300
studies
24%
overlap
4
Promazine
8
shared
40
studies
22%
overlap
5
diphenidol
5
shared
22%
overlap
6
Propafenone
4
shared
14
studies
21%
overlap
9
shared
299
studies
21%
overlap
8
Butylscopolammonium
4
shared
33
studies
21%
overlap
7
shared
300
studies
20%
overlap
8
shared
299
studies
20%
overlap
Shared Biological Targets

Click a target to see all compounds with interactions at that molecular target.

Similarity between compounds is computed using IDF-weighted Jaccard scoring across shared molecular targets in the BiohacksAI BindingDB corpus. Compounds with higher overlap scores share more targets, weighted by how specific those targets are across the entire corpus.

Explore related resources: Diphenhydramine Hcl full profile · Browse all compounds · Biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.