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BiohacksAI/Compounds/Duloxetine/Similar

Compounds Similar to Duloxetine

10 compounds with shared biological targets · BiohacksAI corpus v20260307-01

The compounds below share molecular targets and biological mechanisms with Duloxetine, including interactions with CYP2D6, CYP3A4, CYP1A2. Similarity is calculated using target-weighted Jaccard scoring across the BiohacksAI BindingDB corpus. Higher shared target counts indicate stronger mechanistic overlap.

View Duloxetine profile →DOPAMINE SEROTONIN pathwayNEUROTROPHIC pathway
Similar Compounds — Ranked by Target Overlap
1
Cabergoline
15
shared
299
studies
24%
overlap
2
prochlorperazine
15
shared
24%
overlap
3
fananserin
13
shared
22%
overlap
4
thioridazine
16
shared
22%
overlap
5
Benzethonium
16
shared
96
studies
22%
overlap
6
clemastine
14
shared
22%
overlap
7
ritanserin
14
shared
22%
overlap
8
clomipramine
13
shared
21%
overlap
9
Fluoxetine
19
shared
1,000
studies
21%
overlap
10
brexpiprazole
14
shared
20%
overlap
Shared Biological Targets
HTR2AHTR2BDRD3ADRA2ADRD15-HYDROXYTRYPTAMINEADORA3ADRA1A

Click a target to see all compounds with interactions at that molecular target.

Similarity between compounds is computed using IDF-weighted Jaccard scoring across shared molecular targets in the BiohacksAI BindingDB corpus. Compounds with higher overlap scores share more targets, weighted by how specific those targets are across the entire corpus.

Explore related resources: Duloxetine full profile · Browse all compounds · Biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.