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Compounds Similar to Escitalopram

10 compounds with shared biological targets · BiohacksAI corpus v20260307-01

The compounds below share molecular targets and biological mechanisms with Escitalopram, including interactions with SLC6A4, CYP2C19, CYP2C9. Similarity is calculated using target-weighted Jaccard scoring across the BiohacksAI BindingDB corpus. Higher shared target counts indicate stronger mechanistic overlap.

Similar Compounds — Ranked by Target Overlap
1
pyrilamine
6
shared
43%
overlap
2
azelastine
5
shared
42%
overlap
3
Nefopamheterocyclic
6
shared
299
studies
34%
overlap
5
shared
300
studies
34%
overlap
5
methapyrilene
6
shared
33%
overlap
4
shared
300
studies
33%
overlap
7
amitifadine
4
shared
33%
overlap
8
citalopram
5
shared
31%
overlap
9
bupropion
4
shared
31%
overlap
4
shared
297
studies
30%
overlap
Shared Biological Targets

Click a target to see all compounds with interactions at that molecular target.

Similarity between compounds is computed using IDF-weighted Jaccard scoring across shared molecular targets in the BiohacksAI BindingDB corpus. Compounds with higher overlap scores share more targets, weighted by how specific those targets are across the entire corpus.

Explore related resources: Escitalopram full profile · Browse all compounds · Biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.