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BiohacksAI/Compounds/Guanabenz/Similar

Compounds Similar to Guanabenz

10 compounds with shared biological targets · BiohacksAI corpus v20260307-01

The compounds below share molecular targets and biological mechanisms with Guanabenz, including interactions with 5-HYDROXYTRYPTAMINE, CYP2D6, ADRA1A. Similarity is calculated using target-weighted Jaccard scoring across the BiohacksAI BindingDB corpus. Higher shared target counts indicate stronger mechanistic overlap.

View Guanabenz profile →DOPAMINE SEROTONIN pathwayPROTEOSTASIS pathway
Similar Compounds — Ranked by Target Overlap
1
Oxymetazoline
18
shared
298
studies
39%
overlap
2
Clonidineheterocyclic
16
shared
299
studies
35%
overlap
3
Dexmedetomidine
13
shared
299
studies
33%
overlap
4
Phentolamine
17
shared
300
studies
32%
overlap
5
Methylergonovine
17
shared
193
studies
31%
overlap
6
Yohimbine
18
shared
299
studies
30%
overlap
7
Dihydroergotamine
19
shared
299
studies
29%
overlap
8
Guanfacine
13
shared
294
studies
29%
overlap
9
Trazodone
16
shared
297
studies
29%
overlap
10
Amitriptyline
26
shared
299
studies
29%
overlap
Shared Biological Targets
ADRA2AADRA2CADRA2BADRA1A5-HYDROXYTRYPTAMINEALPHA-2AADRA1DADRA1B

Click a target to see all compounds with interactions at that molecular target.

Similarity between compounds is computed using IDF-weighted Jaccard scoring across shared molecular targets in the BiohacksAI BindingDB corpus. Compounds with higher overlap scores share more targets, weighted by how specific those targets are across the entire corpus.

Explore related resources: Guanabenz full profile · Browse all compounds · Biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.