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BiohacksAI/Compounds/Maprotiline/Similar

Compounds Similar to Maprotiline

10 compounds with shared biological targets · BiohacksAI corpus v20260307-01

The compounds below share molecular targets and biological mechanisms with Maprotiline, including interactions with 5-HYDROXYTRYPTAMINE, CHRM1, ATXN2. Similarity is calculated using target-weighted Jaccard scoring across the BiohacksAI BindingDB corpus. Higher shared target counts indicate stronger mechanistic overlap.

View Maprotiline profile →DOPAMINE SEROTONIN pathwayCORTISOL STRESS pathway
Similar Compounds — Ranked by Target Overlap
1
Nortriptyline
41
shared
295
studies
46%
overlap
2
Amoxapine
43
shared
259
studies
42%
overlap
3
Promethazine
37
shared
296
studies
42%
overlap
4
Domperidone
33
shared
299
studies
37%
overlap
5
Cyproheptadine
37
shared
299
studies
37%
overlap
6
Oxatomide
32
shared
128
studies
36%
overlap
7
Cinnarizinedrugage
27
shared
299
studies
33%
overlap
8
Quetiapine
27
shared
994
studies
32%
overlap
9
Amitriptyline
34
shared
299
studies
32%
overlap
10
Flunarizine
30
shared
299
studies
30%
overlap
Shared Biological Targets
5-HYDROXYTRYPTAMINEADRA1ACHRM1ALPHA-1DALPHA-2ACHRM2CYP2D6ADRB2

Click a target to see all compounds with interactions at that molecular target.

Similarity between compounds is computed using IDF-weighted Jaccard scoring across shared molecular targets in the BiohacksAI BindingDB corpus. Compounds with higher overlap scores share more targets, weighted by how specific those targets are across the entire corpus.

Explore related resources: Maprotiline full profile · Browse all compounds · Biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.