BiohacksAI is an evolving research platform. New compounds and evidence are added continuously.
B
BiohacksAI/Compounds/Pregabalin/Similar

Compounds Similar to Pregabalin

10 compounds with shared biological targets · BiohacksAI corpus v20260307-01

The compounds below share molecular targets and biological mechanisms with Pregabalin, including interactions with CACNA2D1, ADRA1A, CACNA2D2. Similarity is calculated using target-weighted Jaccard scoring across the BiohacksAI BindingDB corpus. Higher shared target counts indicate stronger mechanistic overlap.

View Pregabalin profile →INFLAMMATION pathwayCALCIUM SIGNALING pathway
Similar Compounds — Ranked by Target Overlap
1
Gabapentin
3
shared
295
studies
48%
overlap
2
Salsalate
2
shared
122
studies
21%
overlap
3
Flavin
2
shared
299
studies
17%
overlap
4
Trolox
2
shared
300
studies
17%
overlap
5
Hydromorphone
2
shared
297
studies
16%
overlap
6
obeticholic
3
shared
271
studies
16%
overlap
7
Zanamivir
2
shared
297
studies
15%
overlap
8
Oseltamivir
2
shared
297
studies
15%
overlap
9
Sulfathiazole
2
shared
300
studies
14%
overlap
10
Metformin
3
shared
1,000
studies
14%
overlap
Shared Biological Targets
CACNA2D1MUSRATTUSESR1EUCHROMATICPTGS1PTGS2OPRK1

Click a target to see all compounds with interactions at that molecular target.

Similarity between compounds is computed using IDF-weighted Jaccard scoring across shared molecular targets in the BiohacksAI BindingDB corpus. Compounds with higher overlap scores share more targets, weighted by how specific those targets are across the entire corpus.

Explore related resources: Pregabalin full profile · Browse all compounds · Biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.