BiohacksAI is an evolving research platform. New compounds and evidence are added continuously.
B
BiohacksAI/Compounds/Spironolactone/Similar

Compounds Similar to Spironolactone

10 compounds with shared biological targets · BiohacksAI corpus v20260307-01

The compounds below share molecular targets and biological mechanisms with Spironolactone, including interactions with AR, GLUCOCORTICOID, CYP19A1. Similarity is calculated using target-weighted Jaccard scoring across the BiohacksAI BindingDB corpus. Higher shared target counts indicate stronger mechanistic overlap.

View Spironolactone profile →TESTOSTERONE HORMONES pathwayINFLAMMATION pathway
Similar Compounds — Ranked by Target Overlap
1
Testosterone
22
shared
299
studies
40%
overlap
2
Dihydrotestosterone
20
shared
300
studies
40%
overlap
3
Norethindrone
17
shared
300
studies
39%
overlap
4
Chlormadinone
17
shared
300
studies
38%
overlap
5
Methyltestosterone
16
shared
300
studies
37%
overlap
6
Potassium
15
shared
300
studies
37%
overlap
7
Megestrol
16
shared
300
studies
36%
overlap
8
Dinitrochlorobenzene
22
shared
300
studies
35%
overlap
9
o-Phthalaldehyde
18
shared
300
studies
34%
overlap
10
Medroxyprogesterone
19
shared
299
studies
33%
overlap
Shared Biological Targets
ARCYP3A4ABCB1CYP19A1CYTOCHROMEESR1ESRRACYP2C9

Click a target to see all compounds with interactions at that molecular target.

Similarity between compounds is computed using IDF-weighted Jaccard scoring across shared molecular targets in the BiohacksAI BindingDB corpus. Compounds with higher overlap scores share more targets, weighted by how specific those targets are across the entire corpus.

Explore related resources: Spironolactone full profile · Browse all compounds · Biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.