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B
MOLECULAR TARGETUniProt: O96017

CHEK2

checkpoint kinase 2

28 compounds · BiohacksAI corpus v20260307-01

28
compounds
Compounds
28
Gene Symbol
CHEK2
NCBI Gene
11200

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About CHEK2

CHEK2 (checkpoint kinase 2) is a biological target studied in biomedical research. The BiohacksAI corpus identifies 28 compounds with documented interactions with this target, based on BindingDB assay data and PubMed literature.

View CHEK2 on UniProt →
Compounds Targeting CHEK2 (28)
1
Gefitinib
5.67
confidence
2
Foretinib
4.34
confidence
3
Bosutinib
4.08
confidence
4
Doramapimod
4.06
confidence
5
Bi 2536
4.01
confidence
6
Brigatinib
3.81
confidence
7
Neratinib
3.66
confidence
8
Tae 684
3.43
confidence
9
Mln 8054
3.33
confidence
10
Lestaurtinib
3.04
confidence
11
Pf 03758309
3.00
confidence
12
Hymenialdisine
3.00
confidence
13
Ruboxistaurin
2.94
confidence
14
Defosbarasertib
2.89
confidence
15
Kw 2449
2.64
confidence
16
Gsk 690693
2.64
confidence
17
Ast 487
2.56
confidence
18
Isogranulatimide
2.56
confidence
19
Debromohymenialdisine
2.56
confidence
20
Su 014813
2.20
confidence
21
Prexasertib
2.08
confidence
22
Sra 737
1.95
confidence
23
Ucn 01
1.79
confidence
12
studies
1.10
confidence
11
studies
1.10
confidence
8
studies
1.10
confidence
117
studies
1.10
confidence
300
studies
0.69
confidence
Top 28 compounds by confidence score. Derived from BindingDB assay data.
Data Source
Corpusv20260307-01
SourceBindingDB · ChEMBL · PubMed

All data is computationally derived from published research. Not medical advice. Independent validation required.