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B
MOLECULAR TARGETUniProt: P00374

DHFR

dihydrofolate reductase

17 compounds · BiohacksAI corpus v20260307-01

17
compounds
Compounds
17
Gene Symbol
DHFR
NCBI Gene
1719

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About DHFR

DHFR (dihydrofolate reductase) is a biological target studied in biomedical research. The BiohacksAI corpus identifies 17 compounds with documented interactions with this target, based on BindingDB assay data and PubMed literature.

View DHFR on UniProt →
Compounds Targeting DHFR (17)
1
Gentamicin
6.30
confidence
2
Methotrexate
6.00
confidence
3
Trimethoprim
5.65
confidence
4
Pyrimethamine
5.36
confidence
289
studies
5.02
confidence
6
Diflunisal
4.17
confidence
7
Mefenamic Acid
3.93
confidence
8
Raltitrexed
3.58
confidence
9
Teriflunomide
3.56
confidence
10
Brequinar
3.37
confidence
299
studies
3.14
confidence
12
Dideazafolate
2.40
confidence
13
Pralatrexate
2.08
confidence
300
studies
0.69
confidence
296
studies
0.69
confidence
297
studies
0.69
confidence
298
studies
0.69
confidence
Top 17 compounds by confidence score. Derived from BindingDB assay data.
Data Source
Corpusv20260307-01
SourceBindingDB · ChEMBL · PubMed

All data is computationally derived from published research. Not medical advice. Independent validation required.