BiohacksAI/Targets/MAP2K1

MOLECULAR TARGETUniProt: Q02750

MAP2K1

mitogen-activated protein kinase kinase 1

48 compounds · BiohacksAI corpus v20260307-01

compounds

Compounds

Gene Symbol

MAP2K1

NCBI Gene

5604

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About MAP2K1

MAP2K1 (mitogen-activated protein kinase kinase 1) is a biological target studied in biomedical research. The BiohacksAI corpus identifies 48 compounds with documented interactions with this target, based on BindingDB assay data and PubMed literature.

View MAP2K1 on UniProt →

Compounds Targeting MAP2K1 (48)

Tofacitinib

4.65

confidence

Foretinib

4.34

confidence

Tozasertib

4.33

confidence

Vandetanib

4.30

confidence

Ruxolitinib

4.23

confidence

Bosutinib

4.08

confidence

Neratinib

3.66

confidence

Nintedanib

3.61

confidence

Naphthoquinone

3.58

confidence

Canertinib

3.53

confidence

Pelitinib

3.50

confidence

Tae 684

3.43

confidence

Fedratinib

3.40

confidence

Gilteritinib

3.40

confidence

Trametinib

296

studies

3.22

confidence

Mirdametinib

3.18

confidence

Dovitinib

3.09

confidence

Jnj 7706621

3.09

confidence

Selumetinib

3.09

confidence

Lestaurtinib

3.04

confidence

Hymenialdisine

3.00

confidence

Ci 1040

2.94

confidence

Defosbarasertib

2.89

confidence

Orantinib

2.89

confidence

R 406

2.83

confidence

K 252a

2.83

confidence

Oroidin

2.77

confidence

Pha 665752

2.71

confidence

Plx 4720

2.71

confidence

Kw 2449

2.64

confidence

Linsitinib

2.64

confidence

Cobimetinib

2.64

confidence

Debromohymenialdisine

2.56

confidence

Tak 285

2.40

confidence

Azd 7762

2.30

confidence

Avutometinib

2.30

confidence

Binimetinib

2.30

confidence

Su 014813

2.20

confidence

Amg 900

2.08

confidence

Cep 32496

1.95

confidence

Gsk 1059615

1.95

confidence

Tak 733

1.95

confidence

Pd98059

studies

1.79

confidence

Dasatinib

299

studies

1.10

confidence

Arctigenin

300

studies

0.69

confidence

Axitinib

298

studies

0.69

confidence

Sorafenib

300

studies

0.69

confidence

Vemurafenib

298

studies

0.69

confidence

Top 48 compounds by confidence score. Derived from BindingDB assay data.

Data Source

Corpusv20260307-01

SourceBindingDB · ChEMBL · PubMed

All data is computationally derived from published research. Not medical advice. Independent validation required.