BiohacksAI is an evolving research platform. New compounds and evidence are added continuously.
B
BiohacksAI/Targets/NLRP3
MOLECULAR TARGETUniProt: AAI43360

NLRP3

NLR family pyrin domain containing 3

23 compounds · BiohacksAI corpus v20260307-01

23
compounds
Compounds
23
Gene Symbol
NLRP3
NCBI Gene
114548

Looking for compounds that interact with NLRP3?

View all 23 compounds →
About NLRP3

NLRP3 (NLR family pyrin domain containing 3) is a biological target studied in biomedical research. The BiohacksAI corpus identifies 23 compounds with documented interactions with this target, based on BindingDB assay data and PubMed literature.

View NLRP3 on UniProt →
Compounds Targeting NLRP3 (23)
1
Isoliquiritigenin
4.50
confidence
2
Micheliolide
2.08
confidence
3
Androsterone
300
studies
1.61
confidence
4
Cycloheximide
300
studies
1.61
confidence
5
Dimethyl Fumarate
296
studies
1.61
confidence
6
Etiocholanolone
300
studies
1.61
confidence
7
Hexachlorophene
300
studies
1.61
confidence
8
Lithocholic Acid
300
studies
1.61
confidence
9
Niclosamideorganic
0
studies
1.61
confidence
10
Tyrphostin 9
2
studies
1.61
confidence
11
Calcitriol
300
studies
1.39
confidence
12
Dihydrotestosterone
300
studies
1.39
confidence
13
Ethinyl Estradiol
300
studies
1.39
confidence
14
Thioridazine Hydrochloride
35
studies
1.39
confidence
15
20 Alpha Dihydroprogesterone
224
studies
1.10
confidence
16
Anisomycin
247
studies
1.10
confidence
17
Chlorhexidine
299
studies
1.10
confidence
18
Oridonin
300
studies
1.10
confidence
19
Tocainide
299
studies
1.10
confidence
20
Bortezomib
300
studies
0.69
confidence
21
Disulfiram
297
studies
0.69
confidence
22
Glyburide
298
studies
0.69
confidence
23
Riluzole
298
studies
0.69
confidence
Top 23 compounds by confidence score. Derived from BindingDB assay data.
Data Source
Corpusv20260307-01
SourceBindingDB · ChEMBL · PubMed

All data is computationally derived from published research. Not medical advice. Independent validation required.