BiohacksAI/Targets/SYK

MOLECULAR TARGET

SYK

spleen associated tyrosine kinase

240 compounds · BiohacksAI corpus v20260307-01

240

compounds

Compounds

240

Gene Symbol

SYK

NCBI Gene

6850

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About SYK

SYK (spleen associated tyrosine kinase) is a biological target studied in biomedical research. The BiohacksAI corpus identifies 240 compounds with documented interactions with this target, based on BindingDB assay data and PubMed literature.

Compounds Targeting SYK (50)

Imatinib

5.47

confidence

Foretinib

4.34

confidence

Tozasertib

4.33

confidence

Morin

4.28

confidence

Ceritinib

4.19

confidence

Bosutinib

4.08

confidence

Bi 2536

4.01

confidence

Midostaurin

3.85

confidence

Pazopanib

3.69

confidence

Neratinib

3.66

confidence

Pelitinib

3.50

confidence

Tae 684

3.43

confidence

Fedratinib

3.40

confidence

Gilteritinib

3.40

confidence

Sulfuretin

3.14

confidence

Jnj 7706621

3.09

confidence

At 9283

3.09

confidence

Lestaurtinib

3.04

confidence

Danusertib

2.94

confidence

R 406

2.83

confidence

K 252a

2.83

confidence

Infigratinib

2.77

confidence

Apitolisib

2.71

confidence

Kw 2449

2.64

confidence

Ast 487

2.56

confidence

Raf 265

2.48

confidence

Entospletinib

2.48

confidence

Tyrphostin 47

2.48

confidence

Calphostin C

2.40

confidence

Dasatinib

299

studies

2.30

confidence

Azd 7762

2.30

confidence

Berzosertib

2.30

confidence

Rebastinib

2.20

confidence

Cyc 116

2.08

confidence

Fostamatinib

2.08

confidence

Glesatinib

2.08

confidence

Ouabain

300

studies

1.95

confidence

Cerdulatinib

1.95

confidence

Crizotinib

298

studies

1.79

confidence

Sp600125

117

studies

1.79

confidence

Pf 03814735

1.79

confidence

Ucn 01

1.79

confidence

Anilinopyrimidine1

1.79

confidence

Atorvastatin

1000

studies

1.61

confidence

Simvastatin

1000

studies

1.61

confidence

Amethopterin

289

studies

1.61

confidence

Chlorhexidine

299

studies

1.61

confidence

Clofarabinenucleotide

studies

1.61

confidence

Colchicineheterocyclic

studies

1.61

confidence

Cycloheximide

300

studies

1.61

confidence

Top 50 compounds by confidence score. Derived from BindingDB assay data.

Data Source

Corpusv20260307-01

SourceBindingDB · ChEMBL · PubMed

All data is computationally derived from published research. Not medical advice. Independent validation required.