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BiohacksAI/Targets/TOP2A
MOLECULAR TARGETUniProt: P11388

TOP2A

DNA topoisomerase II alpha

25 compounds · BiohacksAI corpus v20260307-01

25
compounds
Compounds
25
Gene Symbol
TOP2A
NCBI Gene
7153

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About TOP2A

TOP2A (DNA topoisomerase II alpha) is a biological target studied in biomedical research. The BiohacksAI corpus identifies 25 compounds with documented interactions with this target, based on BindingDB assay data and PubMed literature.

View TOP2A on UniProt →
Compounds Targeting TOP2A (25)
1
Doxorubicin Hydrochloride
5.71
confidence
2
Elliptecine
5.21
confidence
3
Amsacrine
4.82
confidence
4
Betulin
4.25
confidence
5
Lupeol
4.03
confidence
6
Hoechst 33258
3.09
confidence
7
Hymenialdisine
3.00
confidence
8
Decernotinib
2.20
confidence
9
Ungeremine
2.20
confidence
10
Merbarone
2.08
confidence
11
Ganoderiol F
2.08
confidence
12
Daunorubicin
298
studies
1.61
confidence
13
Myricetinflavonoids
0
studies
1.61
confidence
14
Topotecan
300
studies
1.10
confidence
15
Teniposide
299
studies
1.10
confidence
16
Ethidium Bromide
300
studies
1.10
confidence
17
Quercetin
300
studies
1.10
confidence
18
Genistein
300
studies
1.10
confidence
19
Aclarubicin
300
studies
0.69
confidence
20
Digitoxin
300
studies
0.69
confidence
21
Dexrazoxane
298
studies
0.69
confidence
22
Epirubicin
300
studies
0.69
confidence
23
Idarubicin
299
studies
0.69
confidence
24
Fisetin
78
studies
0.69
confidence
25
Ciprofloxacin
0
studies
0.69
confidence
Top 25 compounds by confidence score. Derived from BindingDB assay data.
Data Source
Corpusv20260307-01
SourceBindingDB · ChEMBL · PubMed

All data is computationally derived from published research. Not medical advice. Independent validation required.