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BiohacksAI/Compounds/Afatinib/Similar

Compounds Similar to Afatinib

10 compounds with shared biological targets · BiohacksAI corpus v20260307-01

The compounds below share molecular targets and biological mechanisms with Afatinib, including interactions with EPIDERMAL, ABL1, EGFR. Similarity is calculated using target-weighted Jaccard scoring across the BiohacksAI BindingDB corpus. Higher shared target counts indicate stronger mechanistic overlap.

View Afatinib profile →APOPTOSIS pathwayINSULIN SIGNALING pathway
Similar Compounds — Ranked by Target Overlap
1
gefitinib
33
shared
28%
overlap
2
tyrphostin
24
shared
4
studies
25%
overlap
3
erlotinib
31
shared
21%
overlap
4
canertinib
31
shared
20%
overlap
5
vandetanib
29
shared
19%
overlap
6
sb
22
shared
18%
overlap
7
Dasatinib
34
shared
299
studies
17%
overlap
8
Pictilisibdrugage
22
shared
25
studies
16%
overlap
9
Vemurafenib
15
shared
298
studies
16%
overlap
10
cediranib
21
shared
15%
overlap
Shared Biological Targets
ABL1BREAKPOINTARATXN2BLKBRAFARAFMAP3K20

Click a target to see all compounds with interactions at that molecular target.

Similarity between compounds is computed using IDF-weighted Jaccard scoring across shared molecular targets in the BiohacksAI BindingDB corpus. Compounds with higher overlap scores share more targets, weighted by how specific those targets are across the entire corpus.

Explore related resources: Afatinib full profile · Browse all compounds · Biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.