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Compounds Similar to Crizotinib

10 compounds with shared biological targets · BiohacksAI corpus v20260307-01

The compounds below share molecular targets and biological mechanisms with Crizotinib, including interactions with ALK, ABL1, AXL. Similarity is calculated using target-weighted Jaccard scoring across the BiohacksAI BindingDB corpus. Higher shared target counts indicate stronger mechanistic overlap.

Similar Compounds — Ranked by Target Overlap
1
fedratinib
127
shared
34%
overlap
2
tae
130
shared
33%
overlap
3
tozasertib
107
shared
33%
overlap
4
r
119
shared
32%
overlap
5
kw
123
shared
32%
overlap
6
foretinib
101
shared
32%
overlap
7
nintedanib
107
shared
32%
overlap
8
bosutinib
101
shared
31%
overlap
9
lestaurtinib
134
shared
30%
overlap
10
ast
101
shared
30%
overlap
Shared Biological Targets

Click a target to see all compounds with interactions at that molecular target.

Similarity between compounds is computed using IDF-weighted Jaccard scoring across shared molecular targets in the BiohacksAI BindingDB corpus. Compounds with higher overlap scores share more targets, weighted by how specific those targets are across the entire corpus.

Explore related resources: Crizotinib full profile · Browse all compounds · Biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.