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Compounds Similar to Fluoxetine

10 compounds with shared biological targets · BiohacksAI corpus v20260307-01

The compounds below share molecular targets and biological mechanisms with Fluoxetine, including interactions with ADRA1A, CYP3A4, ATXN2. Similarity is calculated using target-weighted Jaccard scoring across the BiohacksAI BindingDB corpus. Higher shared target counts indicate stronger mechanistic overlap.

Similar Compounds — Ranked by Target Overlap
1
risperidone
22
shared
30%
overlap
21
shared
299
studies
29%
overlap
29
shared
299
studies
29%
overlap
4
brexpiprazole
21
shared
28%
overlap
31
shared
299
studies
28%
overlap
28
shared
299
studies
28%
overlap
7
clozapine
22
shared
27%
overlap
8
clemastine
20
shared
27%
overlap
9
niguldipine
20
shared
27%
overlap
28
shared
296
studies
27%
overlap
Shared Biological Targets

Click a target to see all compounds with interactions at that molecular target.

Similarity between compounds is computed using IDF-weighted Jaccard scoring across shared molecular targets in the BiohacksAI BindingDB corpus. Compounds with higher overlap scores share more targets, weighted by how specific those targets are across the entire corpus.

Explore related resources: Fluoxetine full profile · Browse all compounds · Biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.