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BiohacksAI/Compounds/Hydroxyzine/Similar

Compounds Similar to Hydroxyzine

10 compounds with shared biological targets · BiohacksAI corpus v20260307-01

The compounds below share molecular targets and biological mechanisms with Hydroxyzine, including interactions with ADRA1A, ADRB2, CYP2D6. Similarity is calculated using target-weighted Jaccard scoring across the BiohacksAI BindingDB corpus. Higher shared target counts indicate stronger mechanistic overlap.

View Hydroxyzine profile →DOPAMINE SEROTONIN pathwayCIRCADIAN pathway
Similar Compounds — Ranked by Target Overlap
1
Loxapine
20
shared
225
studies
35%
overlap
2
Chlorpheniramine
13
shared
298
studies
33%
overlap
3
risperidone
18
shared
33%
overlap
4
olanzapine
16
shared
31%
overlap
5
Protriptyline
15
shared
296
studies
31%
overlap
6
clozapine
18
shared
31%
overlap
7
Mianserin
24
shared
299
studies
30%
overlap
8
Lidoflazine
19
shared
278
studies
30%
overlap
9
silodosin
13
shared
30%
overlap
10
nantenine
14
shared
30%
overlap
Shared Biological Targets
DRD4ADRA1ADRD2DRD35-HYDROXYTRYPTAMINEHRH1ADRA2BCHRM1

Click a target to see all compounds with interactions at that molecular target.

Similarity between compounds is computed using IDF-weighted Jaccard scoring across shared molecular targets in the BiohacksAI BindingDB corpus. Compounds with higher overlap scores share more targets, weighted by how specific those targets are across the entire corpus.

Explore related resources: Hydroxyzine full profile · Browse all compounds · Biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.