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BiohacksAI/Compounds/Phentolamine/Similar

Compounds Similar to Phentolamine

10 compounds with shared biological targets · BiohacksAI corpus v20260307-01

The compounds below share molecular targets and biological mechanisms with Phentolamine, including interactions with ADRA1A, ADRA1D, ADRA1B. Similarity is calculated using target-weighted Jaccard scoring across the BiohacksAI BindingDB corpus. Higher shared target counts indicate stronger mechanistic overlap.

View Phentolamine profile →DOPAMINE SEROTONIN pathwayINSULIN SIGNALING pathway
Similar Compounds — Ranked by Target Overlap
1
Oxymetazoline
18
shared
298
studies
44%
overlap
2
Clonidineheterocyclic
17
shared
299
studies
41%
overlap
3
Yohimbine
21
shared
299
studies
40%
overlap
4
Guanfacine
15
shared
294
studies
38%
overlap
5
Dexmedetomidine
13
shared
299
studies
38%
overlap
6
Trazodone
18
shared
297
studies
36%
overlap
7
Promethazine
24
shared
296
studies
35%
overlap
8
Dihydroergotamine
19
shared
299
studies
33%
overlap
9
Mianserin
23
shared
299
studies
33%
overlap
10
Guanabenz
17
shared
298
studies
32%
overlap
Shared Biological Targets
ADRA2AADRA2CADRA2BADRA1A5-HYDROXYTRYPTAMINEADRA1BCYP3A4ALPHA-1A

Click a target to see all compounds with interactions at that molecular target.

Similarity between compounds is computed using IDF-weighted Jaccard scoring across shared molecular targets in the BiohacksAI BindingDB corpus. Compounds with higher overlap scores share more targets, weighted by how specific those targets are across the entire corpus.

Explore related resources: Phentolamine full profile · Browse all compounds · Biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.