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BiohacksAI/Compounds/Promethazine/Similar

Compounds Similar to Promethazine

10 compounds with shared biological targets · BiohacksAI corpus v20260307-01

The compounds below share molecular targets and biological mechanisms with Promethazine, including interactions with 5-HYDROXYTRYPTAMINE, CHRM1, ADRA1A. Similarity is calculated using target-weighted Jaccard scoring across the BiohacksAI BindingDB corpus. Higher shared target counts indicate stronger mechanistic overlap.

View Promethazine profile →CORTISOL STRESS pathwayOXIDATIVE STRESS pathway
Similar Compounds — Ranked by Target Overlap
1
Cinnarizinedrugage
33
shared
299
studies
48%
overlap
2
Mianserin
39
shared
299
studies
47%
overlap
3
Amoxapine
44
shared
259
studies
46%
overlap
4
Cyproheptadine
40
shared
299
studies
43%
overlap
5
Nortriptyline
39
shared
295
studies
42%
overlap
6
Maprotiline
37
shared
299
studies
42%
overlap
7
Quetiapine
31
shared
994
studies
41%
overlap
8
Amitriptyline
40
shared
299
studies
40%
overlap
9
Flunarizine
34
shared
299
studies
38%
overlap
10
Trazodone
25
shared
297
studies
37%
overlap
Shared Biological Targets
5-HYDROXYTRYPTAMINEADRA1AADRA2AADRA2CADRA1BCHRM1ALPHA-1DALPHA-2A

Click a target to see all compounds with interactions at that molecular target.

Similarity between compounds is computed using IDF-weighted Jaccard scoring across shared molecular targets in the BiohacksAI BindingDB corpus. Compounds with higher overlap scores share more targets, weighted by how specific those targets are across the entire corpus.

Explore related resources: Promethazine full profile · Browse all compounds · Biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.