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BiohacksAI/Compounds/Rotenone/Similar

Compounds Similar to Rotenone

10 compounds with shared biological targets · BiohacksAI corpus v20260307-01

The compounds below share molecular targets and biological mechanisms with Rotenone, including interactions with ESR1, ESRRA, AR. Similarity is calculated using target-weighted Jaccard scoring across the BiohacksAI BindingDB corpus. Higher shared target counts indicate stronger mechanistic overlap.

View Rotenone profile →OXIDATIVE STRESS pathwayNEUROTROPHIC pathway
Similar Compounds — Ranked by Target Overlap
1
Flutamide
27
shared
298
studies
31%
overlap
2
Lynestrenol
23
shared
299
studies
31%
overlap
3
Niclosamideorganic
37
shared
299
studies
29%
overlap
4
Fenofibrate
23
shared
297
studies
29%
overlap
5
trequinsin
22
shared
1
studies
28%
overlap
6
Idazoxan
23
shared
300
studies
28%
overlap
7
Ethinyl
31
shared
300
studies
27%
overlap
8
Loratadine
28
shared
296
studies
27%
overlap
9
Dactinomycin
25
shared
297
studies
27%
overlap
10
Ethynodiol
21
shared
300
studies
26%
overlap
Shared Biological Targets
ARESR1CYP1A2ESRRACYP2C19CYP2C9CYP3A4FABP1

Click a target to see all compounds with interactions at that molecular target.

Similarity between compounds is computed using IDF-weighted Jaccard scoring across shared molecular targets in the BiohacksAI BindingDB corpus. Compounds with higher overlap scores share more targets, weighted by how specific those targets are across the entire corpus.

Explore related resources: Rotenone full profile · Browse all compounds · Biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.