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BiohacksAI/Compounds/Simvastatin/Similar

Compounds Similar to Simvastatin

10 compounds with shared biological targets · BiohacksAI corpus v20260307-01

The compounds below share molecular targets and biological mechanisms with Simvastatin, including interactions with CYP3A4, CYTOCHROME, ESRRA. Similarity is calculated using target-weighted Jaccard scoring across the BiohacksAI BindingDB corpus. Higher shared target counts indicate stronger mechanistic overlap.

View Simvastatin profile →LIPID METABOLISM pathwayINSULIN SIGNALING pathway
Similar Compounds — Ranked by Target Overlap
1
Nisoldipinedrugage
36
shared
297
studies
32%
overlap
2
Polidocanol
21
shared
299
studies
29%
overlap
3
Flutamide
25
shared
298
studies
29%
overlap
4
Ezetimibe
22
shared
296
studies
29%
overlap
5
Ethynodiol
22
shared
300
studies
29%
overlap
6
Ethinyl
30
shared
300
studies
28%
overlap
7
Melphalan
24
shared
300
studies
28%
overlap
8
Mometasone
23
shared
292
studies
28%
overlap
9
Itraconazole
18
shared
297
studies
28%
overlap
10
Levonorgestrel
21
shared
292
studies
28%
overlap
Shared Biological Targets
ARCHRM1ESR1ESRRAHTR2ACYP1A2CYP2C19NPC1L1

Click a target to see all compounds with interactions at that molecular target.

Similarity between compounds is computed using IDF-weighted Jaccard scoring across shared molecular targets in the BiohacksAI BindingDB corpus. Compounds with higher overlap scores share more targets, weighted by how specific those targets are across the entire corpus.

Explore related resources: Simvastatin full profile · Browse all compounds · Biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.